Mónica Pickholz

Investigadora Independiente de CONICET

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Grupo De Biofisica De Membranas

Área de investigación: Física de materiales

  • Simulaciones computacionales

Intereses

- Interacción de péptidos y fármacos con membranas lipídicas
- Nano encapsulación de fármacos para "Drug Delivery"
- Proteinas de membrana (Concexinas, acuaporinas)

Publicaciones seleccionadas

Last 5 years:

- "Differential Interaction of Antimicrobial Peptides with Lipid Structures Studied by Coarse
Grained Molecular Dynamics Simulations” Galo E. Balatti, Ernesto E. Ambroggio, Gerardo D.
Fidelio, M. Florencia Martini and Mónica Pickholz, Molecules (2017) Oct 20;22(10). pii: E1775.
doi: 10.3390/molecules22101775.

- “ Diblock copolymer bilayers as model for polymersomes: A coarse grain approach” D. Grillo,
J.M.R. Albano, E. Mocskos, J. Facelli, M. Pickholz, and M. Ferraro.The Journal of Chemical
Physics 146, 244904 (2017); doi: http://dx.doi.org/10.1063/1.4986642

- “Naratriptan aggregation in lipid bilayers: perspectives from molecular dynamics simulations”
Irene Wood and Mónica Pickholz, J. Mol. Model. 22, 221 (2016) doi:10.1007/s00894-016-
3096-8.

- “Insights on self-aggregation phenomena of 1-indanone thiosemicarbazones and the formation
of inclusion complexes with hydroxypropyl-?-cyclodextrin by Molecular Dynamics simulations”
M. F. Martini, R.J. Glisoni, A. Sosnik, A. Moglioni and M. Pickholz. Journal of Molecular
Liquids, 222, 963 (2016).

- “Coarse grained study of pluronic F127: Comparison with shorter co-polymers in its interaction
with lipid bilayers and self-aggregation in water” I. Wood, M.F.Martini, J.M.R. Albano, M.L.
Cuestas, V.L. Mathet and M. Pickholz, Journal of Molecular Structure,1109, 106 (2016).

- "Clonidine complexation with hydroxypropyl-beta-cyclodextrin: From physico-chemical
characterization to in vivo adjuvant effect in local anesthesia" M.A. Braga, M.F. Martini, M.
Pickholz, F. Yokaichiya, M.K.D. Franco, L.F. Cabeça, V.A. Guilherme · C.M.G. Silva · C.E.G.
Limia · E. de Paula ·Journal of Pharmaceutical and Biomedical Analysis, 119, 27 (2016).

- “Triptan partition in model membranes” I. Wood and M. Pickholz, Journal of Molecular
Modeling , 20, 2463-2469 (2014).

- “Concentration effects of sumatriptan on the properties of model membranes by molecular
dynamics simulations” I. Wood and M. Pickholz, European Biophysics Journal, 42, 833 (2013).

- “Similarities and Differences of Serotonin and its Precursors in their Interactions with Model
Membranes Studied by Molecular Dynamics Simulations” I. Wood, M.F. Martini and M.Pickholz,
Journal of Molecular Structure, 1045, 124 (2013).

- “Molecular Dynamics Study on the Encapsulation of Prilocaine in Liposomes at Physiological
pH”, Giovanni Giupponi, María Florencia Martini, and Mónica Pickholz, Special Issue
"Nanomedicine in Latin America" of Journal of Biomaterials and Tissue Engineering, 3, 141
(2013).

- “Nicotinamide and picolinamide in phospholipid monolayers” M.F. Martini, E.A. Disalvo and
M. Pickholz, International Journal of Quantum Chemistry, 112, 3289 (2012).

- “Molecular dynamics study of uncharged bupivacaine enantiomers in phospholipid bilayers”,
M.F. Martini and M. Pickholz, International Journal of Quantum Chemistry,112, 3341 (2012).

- “Non-inclusion complexes between riboflavin and cyclodextrins” Marcelo Bispo de
Jesus, Leonardo Fernandes Fraceto, Maria Florencia Martini, Monica Pickholz, Carmen
Veríssima Ferreira, Eneida de Paula, Journal of Pharmacy and Pharmacology, 64, 832 (2012).

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